Overview
The most highly populated island now has over 12,000 residents in the cattle farming communities of the forested highlands and the port Puerto Ayora, which is full of shops, bars and restaurants catering for visitors who board cruise vessels or stay in hotels here. The Charles Darwin Research Station and Galapágos National Park Information Centre are here and the main airport just a short boat ride away on Baltra Island. There are lava tunnels to explore and giant tortoises to spot roaming wild in the mountains.
Holidays Santa Cruz Island (Indefatigable)
From expertly designed Private Journeys to trail-blazing Group Tours, browse our range of carefully crafted holidays.

Private Journeys
Ecuador & Galapagos Islands / Galapagos Islands
Ecuador’s Andes and Galapagos Islands hop
(based on two people sharing & excluding flights)

Private Journeys
Ecuador & Galapagos Islands / Galapagos Islands
Signature Galapagos: Island hopping
(based on two people sharing & excluding flights)

Private Journeys
Ecuador & Galapagos Islands / Galapagos Islands
Value Ecuador and Galapagos: At a glance
(based on two people sharing & excluding flights)

Private Journeys
Ecuador & Galapagos Islands
Walking in Ecuador and Galapagos
(based on two people sharing & excluding flights)
Things to do
We proudly offer the widest range of activities, excursions and one-of-a-kind experiences across all our destinations, tried and tested personally by our travel experts.
Where to go when - our guide to Santa Cruz Island (Indefatigable)

The weather in Santa Cruz Island (Indefatigable) is wide and varied
View our Santa Cruz Island (Indefatigable) weather guidePapagaio
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