Signature Bolivia: The final frontier

Day 1

Transfer to your hotel in a quiet quarter of the city.

Transfer to your hotel, close to the city centre.

The dynamic city of Santa Cruz doesn’t quite reflect how most people imagine Bolivia. With plate glass and concrete, the sparkle of luxury four-wheel drive vehicles, and good restaurants and shopping malls the rapidly growing city wears its new-found oil wealth on its sleeve.

This prosperous lowland metropolis is wholly different from its Andean sisters, in climate, in politics and in ethnic mix. People have poured in from the altiplano to join German Mennonites, Brazilians and even Japanese in search of a better life. The sun can be fierce, the siestas always long, with heavy rain showers in the summer months.

Stay at - Hotel Cortez

Day 2

Guided city tour of cosmopolitan Santa Cruz.

You’ll have a guided tour of the city, purpose-built in a series of rings. You will visit the huge, shady main square, the baroque cathedral which dominates it, and the indigenous Abasto craft shops.

After the tour you might decide to explore the city some more: there are lovely parks with lawns, fountains and street art, tawdry but fascinating street markets selling everything from mobile phones, electric saws to gold jewellery and mangoes, spread over the streets around the handsome colonial core.

Coffee shops, open air bars and ice-cream parlours abound – if you need a breather.

Stay at - Hotel Cortez

Day 3

Transfer by road towards Amboro National Park

Depart Santa Cruz and ascend into the mountains towards Bermejo, within the biodiverse Amboró–Los Volcanes region where Amazonian, Andean and Chaco ecosystems meet. From Bermejo, a short four‑wheel‑drive transfer brings you to Refugio Los Volcanes, set in a private reserve amid striking red sandstone cliffs and dense subtropical forest. On arrival, enjoy a gentle walk to a nearby waterfall before lunch at the lodge.

The afternoon offers guided walks suited to different fitness levels, with opportunities to spot orchids, tree ferns, monkeys and colourful birdlife. A highlight is the Condor Walk, a scenic hike to a natural viewpoint overlooking the forest canopy and dramatic cliffs.

Dinner is served at the lodge, followed by an optional short night walk to experience the sounds, wildlife and clear skies of the forest after dark.

Stay at - Refugio Los Volcanes

Day 4

Choice of guided hikes

If you are looking for a more challenging day on foot, you may choose to take on the Summit Walk – a rewarding hike through the heart of Amboró National Park. The trail leads you through dense forest for the first few hours, immersed in deep, lush vegetation and the constant sounds of the natural world. As you gain altitude, the landscape gradually opens out until you reach a mirador at around 800 metres. From here, the views are spectacular, with sweeping perspectives across the surrounding valleys and, with a little luck, the chance to spot condors circling on the thermals below. This is a demanding walk and requires a very good level of fitness, but the scenery and sense of achievement make it exceptionally worthwhile. A box lunch is included to enjoy along the way.

For those who prefer a gentler pace, alternative hikes and shorter walks are available, allowing you to explore the park’s extraordinary forests and wildlife without the sustained climb.

Stay at - Refugio Los Volcanes

Day 5

El Fuerte and Samaipata

Travel from the cloud-forest setting of Los Volcanes towards one of Bolivia’s most intriguing archaeological sites, El Fuerte de Samaipata. On arrival, you enjoy a guided visit, bringing the site to life with insight into its pre-Inca origins and its later importance to both the Inca and Spanish worlds. Carved directly into the rock, the vast ceremonial platform and surrounding ruins sit dramatically on a hillside, offering wide views across the landscape and a strong sense of the region’s deep cultural layers.

After the visit, you continue on to the small town of Samaipata, where you stop for lunch and have time for a gentle walk through the relaxed streets. The town’s low-key, creative atmosphere and mountain backdrop provide a pleasing contrast to the morning’s archaeological focus.

Later, you are transferred to your hotel, arriving with time to settle in and enjoy the setting at leisure.

Stay at - Hotel El Pueblito

Day 6

Transfer back to Santa Cruz and fly to Sucre

Depart Samaipata and transfer back to Santa Cruz, travelling through changing landscapes as the Andean foothills give way to the city’s broad plains. On arrival at the airport, take a short domestic flight to Sucre, Bolivia’s graceful constitutional capital.

On landing, transfer to your hotel in the city centre. The remainder of the day is at leisure – an ideal opportunity to relax after the journey or to take a first unhurried stroll through Sucre’s whitewashed streets and colonial plazas at your own pace.

Stay at - Parador Santa Maria la Real

Day 7

Guided tour of this elegant, whitewashed colonial city.

Your guided city tour takes you to the Casa de la Libertad, an impressive house on the main square where the declaration of Bolivian Independence was signed in 1825 and La Recoleta, a Franciscan convent which offers splendid views over the valley. It has beautiful cloisters and gardens where an ancient cedar tree still stands. The adjoining chapel is notable for its intricate woodcarvings. In the third cloister is a museum exhibiting sculptures, paintings and other religious works.

You also visit the ASUR indigenous Art Museum – a 17th century colonial building. Exhibits include ancient textiles, musical instruments, costumes and ritual artefacts. A highlight is the Weavers’ Gallery, where you learn about indigenous techniques and designs.

Should you be in Sucre on a Sunday however you’ll be offered an optional (extra cost) excursion to the extraordinary indigenous market at Tarabuco, where the local costume includes a headdress based on the Spanish colonialists’ helmets. Their russet and gold weavings are celebrated worldwide for their intricate embroidery. (In this case the city tour of Sucre will take place the previous day).

Stay at - Parador Santa Maria la Real

Day 8

Climb to the bleak altiplano and Potosí; guided tour and visit imperial Mint.

A scenic 3hr drive to Potosí along a paved road ascending to the high plains of the stark wilderness of the altiplano, passing crops of peas, beans and cereals.

At an altitude of 4,090m Potosí is the highest city in the world. Its former wealth lay in its silver; today it lies in the vestiges of its history and the grand buildings born from a city that was quite literally founded on a mountain of wealth – the Cerro Rico (Rich Hill) with its rich seams of silver.

Today you’ll find ornate churches, monuments, neat cobbled streets and the Casa Real de la Moneda (Royal Mint), one of South America’s finest colonial buildings. The tunnels which honeycomb the Cerro Rico, are as dark and poisonous as the city’s gruesome past.

However, with its narrow streets and grandiose architecture it is one of Bolivia’s great treasure troves. Your walking tour takes you to some of the city’s principal historical attractions. These include San Lorenzo church, with its baroque façade of flesh coloured stone mined from the nearby hills. Inside, works of art adorn the ornate altar along with two original paintings by Holguin.

Also visit Santo Domingo church and the vast 16th century Cathedral.

You’ll also visit the Casa de Real de la Moneda which occupies an entire block near the cathedral. This mint created the currency for the entire Spanish Empire. The museum has a fascinating history, comprising not just the Royal Mint, but also a prison, fortress, and HQ for the Bolivian army during the Chaco War. The museum displays crafted silverware, oil paintings and Bolivia’s first locomotive train.

Stay at - Museo Cayara

Day 9

Drive through skeletal landscapes to Uyuni, overnight in a salt hotel.

Continue by road across the bleak altiplano en route to Uyuni, travelling through dusty landscapes punctuated by weird wind-fashioned rock formations. It is in this region that Butch Cassidy and the Sundance Kid are reckoned to have ambushed hapless folk transporting money and minerals to and from the mines.

Upon arrival in Uyuni you can look around this isolated, chilly highland town and visit the “train cemetery” full of abandoned, rusting engines evocative of more prosperous and dynamic times.

Stay at - Luna Salada

Day 10

Explore the dazzling salt flats and lagoons by 4WD vehicle.

Travel by 4WD vehicle to the Salar de Uyuni. The bleak plains of the southern altiplano make for an austere, uncompromising wilderness, scoured by bitter gales, where cut-glass lakes and un-trodden, luminous salt pans reflect the vast dome of an icy sky.

At 3,650m the salar is the highest salt desert in the world and arguably the largest, covering over 12,000 sq km. When the rains fall, the desert is turned into a mirror, salt plains and sky fuse, and the world is turned upside down. In the dry season, however, the dazzling white of the salt crystals extends as far as the eye can see: an other-worldly sight.

While its few wind-buffeted Aymara inhabitants scratch a meagre living from the dusty soil, there are landscapes of unexpected variety and surreal beauty. You’ll observe desolate, denuded peaks, sunlit lagoons of gem-stone clarity and a white sea of salt that bends the horizon.

Conditions permitting, travel on to the foothills of the Tunupa volcano and the village of Coquesa with its ancient fort and preserved mummies. The road takes you deep into the salar to the Isla de Pescadores, a small volcanic island covered in giant cacti. Return to Uyuni.

Stay at - Luna Salada

Day 11

Transfer to Uyuni airport, fly to the capital, La Paz.

Transfer to the airport for your 1hr flight to La Paz. If it is clear you will have staggering views of the landscape, and will appreciate the vastness of the altiplano.

Set in a deep canyon, dominated by the snow-capped peak of Mount Illimani, La Paz (3,632m) is the highest capital in the world. The colonial core around Plaza Murillo retains much of its quirky Spanish charm, lively with families and children with balloons at the weekend.

Beyond, there are cavernous indigenous markets with restaurant grills open to the street and narrow alleyways lined with museums, churches and craft shops. Ambulant vendors in felt bowler hats and colourful shawls crouch below the skyscrapers in tree-lined modern avenues.

Stay at - La Casona

Day 12

Guided city tour with cable car ride over the canyon.

At first sight La Paz is an anarchic jumble of buildings clinging to craggy slopes and marching down a sinuous river bed.

But partly owing to this topography it’s easy to get around, the streets are tightly packed and crammed with interesting features. A city tour takes you to the narrow lanes around the colonial heart, exploring markets such as the famous Mercado de las Brujas (Witches’ Market) as well as the stately boulevards of the modern business and residential neighbourhoods.

How the city’s structure knits together is best appreciated from the air, and it is now possible for you to enjoy stupendous views from a cable-car erected primarily to relieve traffic congestion on the commuter routes between La Paz city centre and the city of El Alto on the canyon rim, hundreds of metres above. Eventually this system will be the largest urban cable-car network in the world: for now, it has the added asset of being a superb new attraction for visitors.

Stay at - La Casona

Day 13

Drive to lake Titicaca; boat trip to Sun Island, overnight.

It’s a 2.5hr drive (shared tourist transport) to Copacabana on the shores of Lake Titicaca which attracts many pilgrims who make the trip often from great distances on foot.

Lake Titicaca, the world’s highest navigable lake, is also the most sacred in the Andes. Set on the grassy altiplano, it is a body of deep sapphire water lapping shores of fertile silt where cereals and vegetables are cultivated from a surprisingly large number of relatively prosperous indigenous communities. The local people use the swaying tortora reeds to build their traditional boats and even islets and homes (the Uros Islands). The birdlife is abundant and varied, bird-watching can be extremely rewarding here.

You’ll board a hydrofoil to take you across the lake to Moon Island. Visit the Iñak Uyu Sun Virgins temple, considered to be one of the most important ruins on the lake. From there it’s a 10min crossing to Sun Island, birthplace of the Inca gods. Take a scenic walk along Inca trails to your hotel in time for lunch.

You have the afternoon free to explore the island trails, dotted with ancient ruins and tiny villages, and not a car or road in sight.

Stay at - Posada del Inca Isla del Sol

Day 14

Return to La Paz.

Descend to Yamani harbour and visit the Inca stairways and Sacred Fountain, believed to give eternal youth and happiness. Lunch at the archaeological and panoramic Uma Kollo restaurant, which has lake views from its balcony and original Inca walls.

Cross the lake to Copacabana (30mins) before boarding the bus to Huatajata, visiting the Andean Eco-Village at Hotel Inca Utama. The project encompasses all aspects of local culture and nature, and includes reed boat and altiplano museums, a handicrafts workshop, mortuary towers and botanical garden.

Continue back to La Paz (approx 1hr). (Although travelling on shared transport services you will be accompanied by your own guide, who will lead you around the visitor sites on a private basis).

Stay at - La Casona

Day 15

Transfer to airport

Transfer to the airport for your flight home or to your next destination.